Brindine-T
- Combination is more effective in reducing Intra-occular pressure (IOP) compared to the individual drugs used alone
Brimonidine Tartrate
- Only the selective alpha2-adrenergic receptor against approved for chronic treatment in glaucoma
- Ocular hypotensive agent, reduces aqueous humour production and increases uveoscleral outflow
- Offers neuroprotection as it reduces the retinal ganglion cell (RGC) death by up to 50%
Timolol Meleate
- FDA’s “gold standard” drug for IOP reduction
- Beta-adrenergic receptor antagonist decreases the production of aqueous humour, made in the epithelium of the ciliary processes
